henhaobio
Sign in

bioRxivPharmacology & Toxicology

Sperm Toolbox - A selection of small molecules to study human spermatozoa

F. S. Gruber, A. Richardson, Z. C. Johnston, R. Myles, N. Norcross, D. Day, I. Georgiou, L. Sesma Sanz, C. Wilson, K. D. Read, S. Martins da Silva, C. L. Barratt, I. H. Gilbert, J. R. Swedlow

PDFDOIPreprint

Abstract

Male contraceptive options and infertility treatments are limited. To help overcome these limitations we established a small molecule library as a toolbox for assay development and screening campaigns using human spermatozoa. We have profiled all compounds in our automated high-throughput screening platform and provide the dataset, which allows direct side-by-side comparisons of compound effects and assays using live human spermatozoa.

Reproducibility ledger

Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.

Sign in to file a reproducibility report.

Related papers

Similarity Map
SelectedSame fieldCross-field
THISGruber '20Gruber '22Johnston '23Gomez-Olivi '26Sivri '26Doud '25
72% semantic matchDevelopmental Biology
Franz Sebastian Gruber, Zoe C Johnston, Christopher L. R. Barratt+1 more·eLife·Jan 27, 2020· 20 citations