Pan-resistant Candida auris: New York Sub-cluster Susceptible to Antifungal Combinations
B. O'Brien, J. Liang, S. Chaturvedi, J. Jacobs, V. Chaturvedi
Abstract
Four pan-resistant Candia auris strains from New York outbreak were 100% inhibited in vitro by combinations of two antifungal drugs using fixed concentrations achievable in vivo. Pan-resistant C. auris strains have mutations in eleven gene targets associated with major antifungal drugs, and constituted a distinct sub-cluster among NY strains.
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