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GenomicsMicrobial Genomics
Peer-reviewed journal article

Whole Genome Sequence Analysis of Shigella from Malawi Identifies Fluoroquinolone Resistance

George E. StenhouseiD, Khuzwayo C. JereiD, Chikondi PenoiD, Rebecca J. BengtssoniD, End ChinyamaiD, Jonathan J. MandoloiD, Amy K. CainiD, Miren Iturriza‐GómaraiD, Naor Bar‐ZeeviD, Nigel A. CunliffeiD, Jennifer CornickiD, Kate S. BakeriD

Abstract

Increasing antimicrobial resistance and limited alternative treatments led to fluoroquinolone resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterised multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant qnrS1.

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