Topic · Cardiology and Cardiovascular Medicine · Medicine

Cardiac electrophysiology and arrhythmias

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Cell-Type-Resolved Transcriptomics Defines Stable and Accessible Markers of the Cardiac Purkinje Fiber in Sheep and Human Translation

Sabine Charron, Néstor Pallares‐Lupon, Marion Constantin, Jason D. Bayer, Philippe Pasdois, Fanny Vaillant, Richard D. Walton

Laser-capture RNA-seq of sheep Purkinje fibers yields a 331-gene enriched panel; thirteen of sixteen ranked candidates confirmed by RT-qPCR, and CNTN5 is Purkinje-enriched in sheep and human.

bioRxiv · Aug 25, 2026 · PreprintPhysiology✦ In-depth digest

A novel multicellular model of the adult mouse sinoatrial node retains spontaneous electrical activity and enables live investigation of the S100B-associated cell population

Georgiana Luisa Baca, Robert E. Monticone, Bruce D. Ziman, Shah Md Toufiqur Rahman, Pathik Parekh, Sadia Afrin, Christopher Dunn, Richard S. Telljohann, Dongmei Yang, Kwan-Wood Gabriel Lam, Peter Killeen, Dimitrios Tsitsipatis, Ana‐Maria Zăgrean, Myong‐Hee Sung, Nigel H. Greig, , Edward G. Lakatta

Dissociated adult mouse sinoatrial node cultures stay spontaneously electrically active beyond ten days on MEA arrays and, on compliant hydrogels, permit live tracking of heterogeneous S100B-EGFP-labeled cells.

bioRxiv · Jul 20, 2026 · PreprintCell Biology✦ In-depth digest