Topic · Molecular Biology · Biochemistry, Genetics and Molecular Biology
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
94 papers
Tian Yang, Zhixia Ye, Michael Lynch
This paper introduces a multi-agent directed evolution approach that identifies hidden mutations by using multiple substrates, improving enzyme engineering efficiency.
Jorge D. García-García, Jaya Joshi, Jenelle A. Patterson…·Andrew D. Hanson
The paper discusses two systems for continuous directed evolution of enzymes and tests their adaptation for plant enzyme engineering.
Yinglu Cui, Yanchun Chen, Xinyue Liu…·Bian Wu
This paper computationally redesigns PETase to improve its stability and PET degradation efficiency using the GRAPE strategy.
Ramin Fallahzadeh, Bijan Bambai, Nasrin Kamali…·Abbas Akhavan Sepahi
This study improves the specificity of the DszD enzyme through mutagenesis guided by structural predictions and simulations, resulting in increased enzyme activity.