Genetic compatibility and ecological connectivity drive the dissemination of antibiotic resistance genes
David Lund, Marcos Parras-Moltó, Juan Salvador Inda-Díaz, Stefan Ebmeyer, D. G. Joakim Larsson, Anna Johnning, Erik Kristiansson
Random forests using nucleotide-composition dissimilarity and metagenomic co-occurrence predict horizontal transfer of resistance genes between bacteria (general model AUROC 0.873); mismatch limits transfer, human and wastewater co-occurrence favors it.
Nature Communications · Mar 16, 2025Peer-reviewedMicrobiology✦ In-depth digest