Pharmaceutical and Antibiotic Environmental Impacts

Temporal Dynamics Outweigh Fungicide Treatment in Shaping the Turfgrass Phyllosphere Resistome

This study shows that temporal changes in the phyllosphere microbiome have a greater impact on antibiotic resistance gene abundance than fungicide treatment.

Using Arabian Sea Coastal Water as a Model to Study Plasmid-mediated AMR Dissemination driven by Anthropogenic Impacts

The paper studies AMR dissemination in Arabian Sea coastal waters, identifying diverse plasmid replicons and clinically relevant antibiotic resistance genes linked to anthropogenic stressors.

A citywide metagenomic analysis reveals surface-specific microbiome and resistome patterns in outdoor urban environments across Liverpool, UK.

The paper uses shotgun metagenomic sequencing to analyze microbial communities and antimicrobial resistance genes across five urban surface types in Liverpool, finding distinct microbial and resistance profiles with higher ARG abundance on frequently contacted surfaces.

Redox oscillation frequency reshapes antibiotic resistance-gene expression through metabolic and ecological selection in a freshwater community

The paper shows that redox oscillation frequency increases antibiotic resistance gene expression in a freshwater microbial community through metabolic and ecological selection, without altering resistance gene sequences.

Predictors Recover Most of the Metagenomic Signal for Antibiotic Resistance Gene Occurrence: A Cross-City Test of Geographic Transferability in Urban Wastewater

This study uses environmental predictors to predict antibiotic resistance gene occurrence in urban wastewater, achieving 78% of the predictive performance of metagenomic sequencing.

Biochar suppression of antibiotic resistance genes in the soil microbiome

This study evaluates how oak biochar affects antibiotic resistance gene prevalence in soil microbiomes with and without sulphamethazine, showing biochar reduces ARGs through adsorption and community shifts.

Rapid Antimicrobial Resistance Decline Coupled with Microbial Community Shifts in Sewage Polluted River Mesocosms

This study quantifies the rapid decline of antimicrobial resistance genes and microbial community shifts in sewage-polluted river mesocosms under various stress conditions.

Microbial community diversity predicts invasion resistance of freshwater biofilms against antibiotic-resistant bacteria

The paper shows that microbial diversity in river biofilms predicts resistance to invasion by antibiotic-resistant bacteria, with higher diversity reducing the likelihood of establishment.

From sewage to shoreline: Tracing antibiotic resistance gene trends through tropical island wastewater treatment pathways

The paper investigates how microbiome dynamics, chemical exposures, and environmental conditions influence antibiotic resistance gene (ARG) dynamics in wastewater treatment pathways in Guadeloupe.

Effects of different concentrations and combinations of antibiotics on the dynamics of intracellular transposition in Escherichia coli

This study examines how sub-inhibitory concentrations of ceftriaxone, combined with colistin and kanamycin, affect intracellular transposition in Escherichia coli, identifying thresholds for environmental impact.

Bacterial metabolism of synthetic steroids across ecosystems reveals diverse biotransformation products, reactions, and enzymes

This study maps bacterial metabolism of synthetic steroids across ecosystems, identifying transformation products, reactions, and enzymes, and reveals cooperative microbial interactions in steroid metabolism.

A Two-Arm Metabolic-Efflux Adaptation Framework in Klebsiella pneumoniae under Mixed Pharmaceutical Exposure: rutA-Linked Oxidative Entry and rutR-Associated Regulation

This study investigates how Klebsiella pneumoniae adapts to mixed pharmaceutical exposure by identifying oxidative entry and efflux-mediated protection mechanisms.

Cycles of contamination and recovery: Combined sewer overflows drive acute but transient antimicrobial resistance exposure in an urban stream

This study quantifies how combined sewer overflows (CSOs) temporarily increase antimicrobial resistance in urban streams but do not establish long-term resistance due to rapid washout.

Ecological specificity and interconnectivity in Danish environmental resistomes

This study characterizes the Danish environmental resistome across 7,000 samples, identifying core and habitat-specific ARGs and their connectivity across ecosystems.

Bio-based fertilizers shape soil microbiome, resistome and mobilome through metabolism of antibiotic-producing Streptomyces

This study shows bio-based fertilizers containing Streptomyces alter soil resistome and mobilome through ecological restructuring and carbon-dependent microbial activity.

Pulse-driven and persistent antimicrobial resistance markers in a transboundary Great Lakes connecting channel: pulse-week-stratified water-quality thresholds for One Health surveillance

The paper identifies pulse-week-stratified water-quality thresholds for detecting antibiotic resistance genes in the Detroit River, showing distinct source pathways for blaKPC and mecA.

Soil Resistomes in a Tropical Watershed are Indirectly Structured by Bacterial Community Interactions with Soil Properties

The paper investigates how soil properties indirectly shape antibiotic resistance gene (ARG) distribution in a tropical watershed by analyzing microbial community interactions.

Genome-resolved metagenomics reveals the potential for selection for antibiotic resistance due to metal pollution in soil microbial communities near a copper-nickel mine site in Botswana

This study uses genome-resolved metagenomics to show that metal pollution from a copper-nickel mine in Botswana may lead to co-selection of antibiotic resistance genes (ARGs) and metal resistance genes (MRGs) in soil microbial communities.

Reduced antibiotic effect of ciprofloxacin on bacteria in the presence of montmorillonite

This study shows that montmorillonite reduces but does not eliminate ciprofloxacin's growth-inhibitory effect on bacteria in soil environments.

Bacterial Membrane Vesicles in Wastewater Disseminate Antibiotic Resistance Genes

This study isolates bacterial membrane vesicles from wastewater and finds they carry antibiotic resistance genes, persist through treatment, and contribute to antimicrobial resistance spread.

A Multi-Scale Ecological Approach to Assessing Antimicrobial Resistance in a Freshwater Fish

This study assesses antimicrobial resistance in freshwater fish by integrating molecular measurements with geospatial modeling to identify environmental factors linked to AMR gene distribution.

Assessment of the household antibiotic resistance gene, virulence factor genes, and pathogen profiles from three global cities

This study examines antibiotic resistance genes, virulence factors, and pathogens in household environments across three global cities, revealing geographic and spatial variations in microbial profiles.

Urbanisation Reshapes Freshwater Microbiomes: A Systematic Review of Ecological Patterns and Functional Shifts

This paper systematically reviews the impacts of urbanisation on freshwater microbiomes, finding reduced bacterial diversity and increased Proteobacteria, Cyanobacteria, and Coliform bacteria.

SELECT 2.0: Refined and open access SELection Endpoints in Communities of bacTeria (SELECT) method to determine concentrations of antibiotics that may select for antimicrobial resistance in the environment

This paper refines the SELECT method to predict no effect concentrations for resistance (PNECRs) of 32 antibiotics, aiding environmental risk assessments by ranking antibiotics based on their potential to select for antimicrobial resistance.

Using Hi-C and target capture to monitor plasmid transfer in the barley rhizosphere

This study shows plasmid transfer from manure to soil bacteria in barley rhizosphere, but no long-term persistence, with hosts remaining unidentified due to database limitations.

Marine bacterial resistomes integrate ecological adaptation with anthropogenic amplification: genome-resolved insight along a gradient of human impact

This study quantifies how human impact influences marine bacterial antibiotic resistance genes (ARGs) using genome-resolved metagenomics across different environmental gradients.

Combined Antibiotic and Herbicide Pollution Accelerates the Horizontal Transfer of Antibiotic Resistance Genes in Coastal Microbial Communities

Extended-Spectrum and Last-Resort β-Lactams Exert Increasing Impacts on Chicken Manure-Derived Copiotrophic Microbiomes and Resistomes

This study examines how beta-lactamase-resistant antibiotics shape microbial communities and resistance profiles in chicken manure-derived copiotrophic microbiomes compared to earlier beta-lactams and antibiotic-free controls.

Distribution of antibiotic resistance genes across contrasted tropical agroecosystems in Reunion Island

This study assesses antibiotic resistance genes and residues in tropical agroecosystems, finding high ARG prevalence in amended soils and manure, with potential human exposure through food chains.

Protein engineering of a genetically encoded biosensor for wastewater detection of profen NSAIDs

The paper engineers a genetically encoded biosensor, PYRNSAID, to detect profen NSAIDs in wastewater with nanomolar sensitivity and demonstrates its functionality in simulated wastewater matrices.