Ultrasound and Hyperthermia Applications

This study shows that non-invasive ultrasound can deliver GABA to the visual cortex of non-human primates, reducing visual evoked activity, with GABA inhibition being more impactful than BBB disruption.

The paper investigates how ultrasound at 43 MHz affects Piezo1 and NaV1.2 channels, finding that Piezo1 is activated by acoustic streaming while NaV1.2 is not directly affected but may be influenced by heating.

This study shows ultrasound activates brain regions via a cochlear pathway, not directly, by vibrating cerebrospinal fluid connected to the cochlea.

This study shows ultrasound causes cortical activation through an indirect auditory mechanism, not direct neuromodulation at the ultrasound focus.

The paper shows ultrasound induces behavioral responses in C. elegans through mechanical effects on neurons and MEC-4 ion channels, not thermal effects.

This study uses low-intensity focused ultrasound to alter sensory-evoked cortical responses in vivo, showing changes in latency and spatial patterns of neural activity.