Optical Imaging and Spectroscopy Techniques

Compact and contactless reflectance confocal microscope for neurosurgery

This paper introduces a compact reflectance confocal microscope for neurosurgery with high spatial resolution and potential for label-free, contactless use.

Improved estimation of hemodynamic response in fNIRS using protocol constraint and wavelet transform decomposition based adaptive algorithm

The paper introduces a wavelet-based adaptive algorithm to improve hemodynamic response estimation in fNIRS by incorporating protocol constraints and Kalman filtering.

Improving model-based fNIRS analysis using mesh-based anatomical and light-transport models

The paper improves fNIRS analysis by developing a surface-based meshing pipeline for creating high-quality brain models, showing significant improvements in accuracy over existing methods.

NIR-II fluorescence microscopic imaging of cortical vasculature in non-human primates

The paper develops NIR-II fluorescence microscopy techniques to image cortical vasculature in non-human primates, enabling high-resolution analysis of brain microvascular networks and blood flow.

Cerebral oxygenation during locomotion is modulated by respiration

This study shows that locomotion increases cerebral oxygenation in mice, and this increase is linked to respiration rate and phase.

Transcranial recording of electrophysiological neural activity in the rodent brain in vivo using functional photoacoustic imaging of near-infrared voltage-sensitive dye

This paper demonstrates the use of functional photoacoustic imaging with a near-infrared voltage-sensitive dye to record in vivo neural activity in rats without craniotomy, showing distinguishable responses in seizure models.

The timing of hemodynamic changes reliably reflects spiking activity

This study shows that the timing of hemodynamic initial-dip and response better reflects spiking activity than amplitude in anesthetized monkeys.

The hemodynamic initial-dip consists of both volumetric and oxymetric changes correlated to localized spiking activity

This study identifies the initial-dip in neuroimaging signals as primarily driven by a decrease in total-hemoglobin, coupled to localized spiking activity.

Measuring speaker-listener neural coupling with functional near infrared spectroscopy

This study measures brain-to-brain coupling during verbal communication using fNIRS and finds it correlates with fMRI in speech comprehension areas, suggesting fNIRS as a reliable and portable tool for studying communication.