YBX3 overexpression in mesothelioma drives aberrant cell proliferation
Angela Rubio, Robert F. Harvey, Andrew Craxton, Mark R. Southwood, Catherine Ficken, Catarina de Matos Ferraz Franco, Lajos Kalmar, Gorettu Munoz, Ian R. Powley, Stephan Kamrad, Rui Guan, David Fernández‐Antorán, Kiran Raosaheb Patil, John P. C. Le Quesne, Marion MacFarlane, Anne E. Willis
This study identifies YBX3 as an oncoprotein in mesothelioma that drives cell proliferation through SLC7A5/LAT1-mediated amino acid uptake and shows JPH203 as a potential therapeutic agent.
Cell Death and Disease · Oct 30, 2026Peer-reviewedMolecular Biology