Author

Meredith S. Gwin

Yale UniversityORCID 0000-0002-3084-8032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Edward P. ManningiD· 3 shared Jack Di PaloiD· 3 shared Jason M. SzafroniD· 2 shared Liqin LiniD· 2 shared Nicole M. Guerrera· 2 shared Rira ChoiiD· 2 shared Xiting YaniD· 2 shared A. JustetiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersPhysiology

Edward P. ManningORCID

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Author profile →

3 papers

Recent·Most cited

Crystalline silica exposure causes latent biomechanical abnormalities along the cardiopulmonary axis

Meredith S. Gwin, Jack Di Palo, Anthony A. Fung, Rira Choi, Péter Hermán, Alexandria Regan, Aishani Nagamalla, Asad A Syed, Theodore Sandow, Ying Sun, Sydney L. Bluestein, Buqu Hu, Yo Sep Shin, Keshav Harpavat, Clemente J. Britto, , Edward P. Manning

This study shows that a single crystalline silica exposure causes subclinical cardiopulmonary abnormalities in mice, with sex-dependent effects on lung mechanics and transcriptomic responses.

bioRxiv · Oct 24, 2026 · PreprintPhysiology

Inherent Biomechanical Properties of the Lung: In vivo-Ex vivo Comparisons in Mice

Jack Di Palo, Jonathan T. Ibinson, Liqin Lin, Bryan Suh, Meredith S. Gwin, Sandra E. Zaeh, Jason M. Szafron, Edward P. Manning

This study compares in vivo and ex vivo lung biomechanics in mice, finding that thoracic structures mainly affect dynamic dissipation and heterogeneity rather than intrinsic elastic properties.

bioRxiv · Jun 29, 2026 · PreprintPhysiology

Biological Aging of the Cardiopulmonary System

D K Liu, Pramath Doddaballapur, Zhongyu Cai, Rira Choi, Jack Di Palo, Nicole M. Guerrera, Nebal Abu Hussein, Meredith S. Gwin, Liqin Lin, Siming Zheng, Yuening Zhang, A. Justet, Abhay B. Ramachandra, Xiting Yan, Edward P. Manning

This study quantifies biological cardiopulmonary aging in mice by integrating biomechanics and single-cell transcriptomics, revealing non-linear aging patterns and cell-type-specific gene expression changes.

bioRxiv · Jun 12, 2026 · PreprintPhysiology