Topic · Epidemiology · Medicine

Nonmelanoma Skin Cancer Studies

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

3 papers

Inflammasome Activation in Cutaneous Squamous Cell Carcinoma

Ruochong Wang, Kush R. Patel, Raphael R. Shu, Khushi Tekale, Michael Hamersky, Adelaida B. Perez, David Solano, Nooreen Syed, Connor E. Stewart, Joseph Lee, Allison M. Hanlon, Travis Wayne Blalock, Chaoran Li, Lindsey Seldin

This study investigates inflammasome activation in cutaneous squamous cell carcinomas, finding it occurs in both epithelial and dermal compartments and involves fibroblast IL-1 signaling.

Molecular Biology of the Cell · Jan 15, 2026Peer-reviewedCell Biology

Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma

Bishal Tandukar, Delahny Deivendran, Limin Chen, Aravind K. Bandari, Noel Cruz‐Pacheco, Harsh Sharma, Meng Wang, Albert Xu, Daniel B. Chen, Christopher D. George, Annika L. Marty, Raymond Jaihyun Cho, Jeffrey B. Cheng, Drew K. Saylor, Pedram Gerami, , Alan Hunter Shain

This study uses multi-omic profiling to trace molecular changes in skin cells during carcinogenesis, identifying key mutations and spatial gene expression patterns in keratinocytes, actinic keratoses, and squamous cell carcinomas.

Nature Communications · Nov 27, 2025Peer-reviewedGenomics

Wounding triggers invasive progression in human basal cell carcinoma

Laura Yerly, Massimo Andreatta, J. Garnica, Charles Nardin, J. Di Domizio, François Aubin, M. Gilliet, S. J. Carmona, François Kuonen

This study shows that wounding, such as biopsy, triggers invasive progression in human basal cell carcinoma by activating a wound response gene program and reprogramming cancer-associated fibroblasts.

Journal of Investigative Dermatology · Jul 21, 2025Peer-reviewedCancer Biology