Polyomavirus and related diseases

High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms

This study identifies two MCPyV integration patterns in MCC and links them to NHEJ and MMBIR mechanisms, showing integration preference for open chromatin and viral promoter-driven oncogene expression.

Detection of Merkel cell polyomavirus using whole exome sequencing data

The paper presents a bioinformatics method to detect Merkel cell polyomavirus insertions in whole exome sequencing data of Merkel cell carcinoma samples, achieving 100% sensitivity and 62.5% specificity.

DETECTing Merkel cell Polyomavirus in Merkel Tumours

This paper develops a CRISPR-based diagnostic tool to detect Merkel cell polyomavirus in Merkel cell carcinomas with high sensitivity and specificity.

Stochastic model of BKPy Virus replication and assembly

The paper develops an agent-based computational model of BKPyV replication and assembly in salivary gland cells, revealing that slow replication may result from capsid subunit accumulation rates and salivary gland-specific transcription factors.