Retinopathy of Prematurity Studies

Targeting endothelial ERG to mitigate vascular regression and neuronal ischemia in retinopathies

This study shows that overexpressing ERG in endothelial cells prevents vascular regression and neuronal damage in OIR models, suggesting ERG as a potential therapeutic target for retinopathies.

Corticosteroids prevent pathological angiogenesis yet compromise reparative vascular remodeling in the retina

This study shows corticosteroids inhibit early pathological angiogenesis but hinder reparative vascular remodeling in retinopathy.

Environmental Oxygen Regulates Astrocyte Proliferation to Guide Angiogenesis during Retinal Development

This study shows that environmental oxygen levels affect astrocyte proliferation, which in turn impacts retinal angiogenesis and contributes to vascular disorders like ROP.