Jeremy N. Kay

This study shows that restoring the CRB1-B isoform in photoreceptors rescues retinal degeneration in a mouse model of CRB1 disease by preserving adherens junctions.

The paper shows that phosphatidylserine exposure by developing astrocytes triggers microglia-mediated cell death, leading to vascular defects in the retina and cerebral cortex.

The paper identifies development-specific microglial populations in the mouse retina using single-cell RNA-seq and validates their roles in retinal development.

The paper shows that dendrite-soma exclusion mediated by MEGF10 establishes mosaic spacing in mouse retinal starburst amacrine cells.

The paper shows that FLRT2-UNC5 signaling mediates synaptic partner rejection in retinal neurons by eliminating dendrites that stray from their correct sublayers.

This study shows that environmental oxygen levels affect astrocyte proliferation, which in turn impacts retinal angiogenesis and contributes to vascular disorders like ROP.

This study shows that Thrombospondin-1 promotes circuit-specific synapse formation in direction-selective retinal ganglion cells via β1-integrin.

The paper shows that retinal astrocytes undergo large-scale death during development, mediated by microglia rather than apoptosis, leading to anatomical and functional changes in the retinal network.

The paper shows that starburst amacrine cells use homotypic contacts to initiate formation of a dendritic scaffold in the retina, which is critical for direction-selective circuitry.