Microbial Metabolites in Food Biotechnology

Fructooligosaccharide Supplementation Improves Glucose Homeostasis in Human-Relevant hyperglycemic Diet-Induced Obese Mice

This study shows that fructooligosaccharide (FOS) improves glucose homeostasis and reduces weight gain in diet-induced obese mice without reducing food intake.

From FODMAPs to prebiotic candidates: enzymatic transglycosylation of raffinose oligosaccharides towards new mixed-linkage oligosaccharides

This paper uses β-galactosidase to convert raffinose oligosaccharides into β-GOS, which are less fermentable by some gut microbes but still usable by beneficial bacteria.

Donor Age and Oligosaccharide Structure Jointly Shape the Gut Microbiome Function

The paper investigates how oligosaccharide structure and donor age influence gut microbiome function through ex vivo fermentation, metaproteomics, and metabolomics.

Spray Dried Inulin-Montmorillonite Hybrids Alleviate High-Fat Diet-Induced Inflammatory and Metabolic Dysregulation in Rats

This paper evaluates a spray-dried inulin-montmorillonite hybrid that reduces free fatty acid release and weight gain in HFD-fed rats, while promoting beneficial gut microbiota changes.

Prebiotic Potential of Non-digestible Oligosaccharides Isolated from Barnyard Millet (Echinochloa frumentacea ) Grain

This study isolates and characterizes non-digestible oligosaccharides from barnyard millet, showing their prebiotic potential through fermentation and probiotic activity.

In Vitro Prebiotic Potential of Purified Black Rice Oligosaccharides: Simulated Digestion Stability, Short-Chain Fatty Acid Production, and Probiotic Biofilm Formation

This study evaluates the prebiotic potential of purified black rice oligosaccharides, showing their resistance to digestion, promotion of SCFA production, and enhancement of probiotic biofilm formation.

Prebiotic ALPINA GOS produced from whey permeate has a bifidogenic effect on the adult fecal microbiota in vitro, including stimulation of organic acids production

This study produces ALPINA GOS from whey permeate and shows it stimulates beneficial bacteria and organic acid production in vitro.

Microbiome-Dependent Functional Responses to Structurally Distinct Oligosaccharides Revealed by Metaproteomics

The paper uses metaproteomics to show that gut microbiomes have personalized functional responses to different oligosaccharides, highlighting the need for individualized prebiotic strategies.