Diphtheria, Corynebacterium, and Tetanus

Comparative genome analysis of Corynebacterium ulcerans Japanese isolates revealed domestically and globally diverse geographical distribution of the organism of different types.

The paper analyzes over 700 genomes of Corynebacterium ulcerans and C. ramonii isolates to reveal geographic differences in sequence types and toxigenic prophage compositions, with ST337 predominating in Japan and associations between prophage types and toxin production.

Description of two novel Corynebacterium species isolated from human nasal passages and skin

This paper describes two novel Corynebacterium species isolated from human nasal passages and skin, along with characteristics of two strains of a recently named species.

Genus-wide re-speciation of Corynebacterium and genomic characterisation of 87 sinus isolates resolves taxonomic conflicts and identifies four candidate novel species

The paper re-speciates Corynebacterium using genome data from 87 isolates and identifies four novel species candidates, resolving taxonomic conflicts and clarifying functional roles.

Skin and Gut Microbiome Features Associated with Resistance to Corynebacterium bovis-Associated Disease in Nude Mice (Mus musculus)

This study identifies microbiome features associated with resistance to Corynebacterium bovis-associated disease in mice by comparing skin and gut microbiomes across different donor sources.

Microbiome-Dependent Protection Against Corynebacterium bovis-Associated Hyperkeratosis in Nude Mice (Mus musculus)

This study shows that the microbiome can protect against C. bovis-induced hyperkeratosis in nude mice, with specific microbiome compositions reducing disease severity.

Modified Elek test improves in-vitro detection of diphtheria toxin

The study modifies the Elek test to improve detection of diphtheria toxin in Corynebacterium species, identifying more toxigenic isolates previously classified as non-toxigenic.

Life identification number (LIN) codes for the genomic taxonomy of Corynebacterium diphtheriae strains

This paper introduces a hierarchical genomic taxonomy system for Corynebacterium diphtheriae using cgMLST-based Life Identification Number (LIN) codes to classify strains at multiple levels of resolution.

A novel strategy to mitigate Corynebacterium bovis-associated hyperkeratosis (CAH) in athymic nude mice

This study evaluates whether non-pathogenic Cb or Ca can prevent CAH in nude mice, finding that Ca inoculation reduced lesion severity and delayed onset.

Population structure and antimicrobial resistance of Corynebacterium diphtheriae in Victoria, Australia

This study analyzes the population structure and antimicrobial resistance of C. diphtheriae isolates from Victoria, Australia, revealing genetic diversity and multidrug resistance in contemporary isolates.

Revealing the diversity of commensal corynebacteria from a single human skin site

The paper identifies 7 Corynebacterium species and 2 novel species from a single human skin site using long-read sequencing and pangenome analysis.

Genomic Epidemiology and Microevolution of the Zoonotic Pathogen Corynebacterium ulcerans

This study develops a cgMLST scheme for high-resolution genotyping of C. ulcerans and identifies genetic clusters linked to transmission and geographical spread.

The Impact of Host Genetics and/or its Microbiota on the Severity of Corynebacterium-Associated Hyperkeratosis in Outbred Athymic Nude Mice

This study investigates how host genetics and microbiota affect the severity of Corynebacterium-associated hyperkeratosis in nude mice, finding that certain stocks show resistance while others develop significant disease.

The exoproteome and surfaceome of toxigenic Corynebacterium diphtheriae 1737 and its response to iron-restriction and growth on human hemoglobin

This study identifies iron-dependent changes in the exoproteome and surfaceome of C. diphtheriae 1737, revealing virulence factors involved in heme acquisition and host interaction.

Taxonomic classification of strain PO100/5 shows a broader geographic distribution and genetic markers of the recently described Corynebacterium silvaticum

The paper reclassifies strain PO100/5 as Corynebacterium silvaticum, identifies genetic markers, and shows its geographic and genetic distinctiveness from other strains.