Medicinal Plants and Neuroprotection

Anti Alzheimer's effects of Neem oil nanoemulsion against Amyloid β1-40 induced in human neuroblastoma SH-SY5Y cell line

This paper evaluates the anti-Alzheimer's effects of neem oil nanoemulsion on amyloid β1-40-induced SH-SY5Y cells, showing improved cytotoxicity reduction compared to neem oil.

Multi-omics analysis in mouse primary cortical neurons reveals complex positive and negative biological interactions between constituent compounds in Centella asiatica

The paper investigates compound interactions in Centella asiatica using multi-omics analysis on mouse neurons, revealing both positive and negative effects on gene and metabolite profiles.

Comprehensive Invitro and Insilico Analysis of Secondary Metabolites from Datura metel: Promising Anti-Alzheimer's Therapeutics.

This paper identifies potential anti-Alzheimer's compounds from Datura metel through in vitro and in silico analysis, highlighting Luteolin and Withanolide A as promising candidates.

Asiatic acid improves mitochondrial function, activates antioxidant response in the mouse brain and improves cognitive function in beta-amyloid overexpressing mice.

This study shows Asiatic acid improves mitochondrial function, antioxidant response, and cognitive performance in mice, with gender-specific effects on reducing amyloid plaques.

Small molecules from Bacopa monneiri as potent inhibitors against Neurodegenerative disorders

The paper evaluates the pharmacological effects of Bacopa monnieri phytochemicals using in-silico methods to identify potential inhibitors of amyloid-β plaques.

Beneficial effects of two Ayurvedic formulations, Saraswata Ghrita and Kalyanaka Ghrita on survival and on toxic aggregates in Drosophila models of Huntington's and Alzheimer's disease

This study evaluates two Ayurvedic formulations in Drosophila models of Huntington's and Alzheimer's disease, showing improved survival and reduced toxic aggregates at low concentrations.