Author

Samantha Varada

Oregon Health & Science UniversityORCID 0009-0000-0784-5442Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Joseph F. QuinniD· 2 shared Noah Gladen-Kolarsky· 2 shared Nora E. GrayiD· 2 shared Wyatt R. HackiD· 2 shared Barbara Hagenah BrumbachiD· 1 shared Christopher Harris· 1 shared Finch Klein· 1 shared Gisselle A. JimeneziD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Joseph F. QuinnORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 5, 2026

The TREM2 targeting small molecule Sob-AM2 improves cognition independent of Aβ plaque alteration in 5xFAD mice

Lucas Kuhnau, Gisselle A. Jimenez, Wyatt R. Hack…·Nora E. Gray

Sob-AM2 improves cognition in 5xFAD mice without altering Aβ plaque burden, suggesting TREM2-mediated microglial changes may underlie its effects.

DOI 10.64898/2026.07.31.741838

mouseexperimental assay

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NeurosciencebioRxivPreprintFeb 21, 2024

Asiatic acid improves mitochondrial function, activates antioxidant response in the mouse brain and improves cognitive function in beta-amyloid overexpressing mice.

Samantha Varada, Steven R. Chamberlin, Lillie Bui…·Nora E. Gray

This study shows Asiatic acid improves mitochondrial function, antioxidant response, and cognitive performance in mice, with gender-specific effects on reducing amyloid plaques.

2 citations

mouseproteomics

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