Vitamin K Research Studies

Vitamin K2 Limits Ferroptosis-Associated Lipid Peroxidation and Attenuates Aortic Valve Stenosis

This study shows vitamin K2 reduces ferroptosis-driven lipid peroxidation and slows aortic valve stenosis progression in both human and mouse models.

The vitamin K oxidoreductase VKORC1L1 prevents oxidative stress in hepatocytes and protects from MASLD and hepatocellular carcinoma

This study identifies VKORC1L1 as a hepatic antioxidant that prevents oxidative stress and protects against MASLD and hepatocellular carcinoma by reducing vitamin K.

Structural and Functional Insights into GGCX-FIX Interaction: Implications for Vitamin K-Dependent Bleeding Disorders

This study identifies key functional regions of GGCX and their interactions with FIX using AlphaFold 3 and simulations, revealing residues critical for carboxylation and vitamin K epoxidation.