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The paper introduces a fluorescent calcium biosensor with ultra-slow response kinetics, useful for applications where delayed signal detection is advantageous.

This paper develops tissue-derived insoluble type I and type II collagen inks for 3D printing of scaffolds, showing viable cell responses and dimensional stability.

The paper develops injectable nanoparticles that form soft, functionally segmented brain electrodes capable of neuronal stimulation and gene transfer in chicken embryos.

This study examines how physical exercise affects osteocyte lacunar morphology and orientation around bioresorbable implants in rats, showing increased lacunar size and altered orientation with exercise.

This study investigates how perceptual sensitivity and errors contribute to locomotor adaptation, finding that sensitivity drives initial motor corrections while errors predict motor aftereffects.

This paper introduces a mesoscale soft robotic interface to apply mechanical forces to human organoids and monitor their physiological responses, revealing distinct mechanical and electrophysiological behaviors in cortical and cardiac organoids.

This paper introduces Live-ST, a method for longitudinal spatial transcriptomics, and demonstrates its use in tracking drug response in melanoma tissues.

This paper demonstrates that a genomic language model can generate functional regulatory DNA sequences using few examples, showing improved performance in cell-type-specific gene expression and neuronal labeling.

This paper introduces a non-destructive 3D bone mineralisation assay using human dental pulp stem cell spheroids, showing a 13.74-fold assay window and Z-factor of 0.627.

The paper introduces ART, a physical theory for designing solid-phase immunoassays by modeling coupled processes and demonstrating its application through examples.

This study identifies genomic and environmental factors affecting circular single-stranded DNA (cssDNA) yield in engineered E. coli and improves production efficiency.

CountAnywhere provides a smartphone-based tool for accurate and efficient cell counting and viability assessment using hemocytometer images.

This study shows that matrix stiffness influences breast cancer cell dormancy states, with soft matrices inducing transient dormancy and stiff matrices causing prolonged dormancy.

This paper uses HiP-CT to image the human spine at high resolution, revealing multiscale anatomy and microstructural features without exogenous contrast.

This paper uses AI agents to design and refine CAR intracellular domains, resulting in a compact ICD that improves CAR expression and function.

This study develops sex- and disease-informed biomaterial design criteria from human lung tissue to create engineered hybrid-hydrogels that recapitulate mechanical and biochemical features of IPF.

This study uses femtosecond laser ablation to measure collagen fiber recoil in tendons, showing that hyaluronic acid (HA) is critical for fiber sliding and mechanical properties.

This paper introduces a multimodal microscope that uses a cGAN to generate virtual fluorescence images from phase contrast data, enabling virtual histological staining of bulk tissues.

This study uses a subject-specific musculoskeletal model to examine how load magnitude, height, and side affect spinal loading and muscle forces in adolescent idiopathic scoliosis.

This study uses functional ultrasound imaging to map brain and spinal cord activity during micturition in rats, revealing region-specific hemodynamic responses and decoding bladder pressure dynamics.