Discover, rate, and discuss biology preprints.

This study examines how maize introduction to Europe shaped genetic diversity and differentiation, finding landraces maintain high diversity despite selection pressures and modern breeding accumulating genetic load.

This study reconstructs the evolutionary changes in tetrapod mandible structure across 3047 species, finding rapid canalization of jaw morphology at key clades and a decrease in compositional disparity over time.

The paper analyzes molecular evolutionary patterns of gustatory receptors in Anopheles gambiae complex mosquitoes to identify genes under positive selection associated with host preference and adaptation.

The paper quantifies the effects of genes, environment, and development on human behavior using in-silico methods and finds developmental history has a greater impact than genetics or environment.

This study identifies proto-MHC-like regions in the sea lamprey genome, showing synteny with human MHC and amphioxus proto-MHC, but lacking core MHC genes.

The paper identifies three yeast lineages with reduced DNA repair genes and high evolutionary rates, showing how gene loss can lead to persistent hypermutator phenotypes.

This study shows that the timing of starvation affects Drosophila melanogaster's susceptibility to E. faecalis infection, with post-infection starvation improving survival regardless of prior treatment.

The paper examines the role of a supergene haplotype in supercolonial Formica ants and finds it absent in supercolonial populations despite its association with polygyny.

This study develops mathematical models to explore how chemotherapy and immune checkpoint blockade (ICB) combination therapy affects heterogeneous tumors, revealing chemotherapy's role in reducing antigenic heterogeneity and enhancing ICB efficacy through immune recovery.

This study shows gene expression plasticity in yeast is adaptive under antibiotic stress but neutral under osmotic stress, using mutation accumulation lines to distinguish selection effects.

This study investigates the genetic basis of vertical bar evolution in clownfish by analyzing changes in selective pressure on pigmentation-related genes.

This study reconstructs hormone-bHLH regulatory networks in Solanaceae, showing evolutionary changes in bHLH genes and regulatory rewiring under PSTVd infection in tomato.

The study presents a chromosome-level genome assembly of the Atlas blue butterfly, revealing constraints on chromosome evolution in Lepidoptera through extensive fission and fusion events.

This paper models compositional and exchange rate heterogeneity in molecular evolution and compares their detection using Bayesian models and matched pairs tests.

This study shows how polyploidy in Brachypodium hybridum enhances drought adaptation through genomic legacies and subgenome expression biases.

The paper applies phylogenetic location-scale models to leaf economic data in Eucalyptus, showing that incorporating trait variance improves predictions of niche conservatism and ecological adaptation.

The paper models how branching architecture influences within-individual genetic diversity in trees by analyzing the effects of two parameters on mutation accumulation.

This study identifies lipocalins in mosses as regulators of development and stress response, revealing their conserved function across land plants.

This study identifies 683 miRNAs in cavefish, revealing their role in regulating development and metabolism through differential expression and pathway involvement.