Yoichi Sut­oh

Osteoporosis Genetic Risk Prediction Using Bone Mineral Density Polygenic Scores in Japanese: TMM CommCohort Study

The paper develops and validates a polygenic score for osteoporosis in Japanese individuals using heel quantitative ultrasound data, showing genetic risk stratification.

Polygenic Risk Score Stratification Guides Prioritization of Modifiable Risk Factors for Stroke Prevention

This study shows that modifiable risk factors have varying impacts on stroke risk depending on genetic predisposition, with higher genetic risk amplifying the effect of these factors.

Real-world data from the Japanese National Health Insurance System enable fine phenotyping in a 14K-scale population-based study

The paper uses Japanese health insurance claims data to improve disease prevalence estimation and GWAS results for Alzheimer's and Parkinson's diseases.

Proto-MHC signatures in the lamprey genome

This study identifies proto-MHC-like regions in the sea lamprey genome, showing synteny with human MHC and amphioxus proto-MHC, but lacking core MHC genes.

A Pro-Diabetogenic mtDNA Polymorphism in the Mitochondrial-Derived Peptide, MOTS-c

The paper identifies a mtDNA polymorphism in MOTS-c associated with increased T2D risk in males, interacting with physical activity.