Yao Yu

The paper enhances glycoprotein secretion in yeast by engineering a human-like protein quality control system, resulting in up to 12-fold increased production of therapeutic glycoproteins.

This study transfers chromosomes from Saccharomyces cerevisiae to Kluyveromyces marxianus, resulting in improved phenotypes and widespread transcriptional changes.

This study shows gene expression plasticity in yeast is adaptive under antibiotic stress but neutral under osmotic stress, using mutation accumulation lines to distinguish selection effects.

This paper develops a yeast artificial chromosome system in K. marxianus to enhance heterologous protein expression by incorporating disulfide bond formation modules, achieving record-high glucoamylase yields.