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The paper develops a pan-generic 3K DArTag marker panel for Malus species to enable genetic research and breeding, showing strong cross-species transferability and utility for QTL mapping and marker-assisted selection.

This study identifies and characterizes lncRNAs in Mucorales fungi, revealing their roles in development and pathogenicity, and highlights their potential as antifungal targets.

This study investigates the role of Resilin in Drosophila flight and jumping, showing that its knockdown impairs wing movement and reduces jump distance, with Duox playing a critical role in its polymerization.

The paper uses sex-stratified analyses to explore genetic architecture of complex traits in mice and humans, finding high concordance in allelic effect directions and suggesting new methods for identifying biologically significant associations.

Nephrobase Cell+ is a kidney-specific foundation model that outperforms existing models in single-cell analysis, cross-species transfer, and batch effect correction.

This study shows that bco1l is essential for VA production in betta fish larvae, leading to developmental defects when knocked out.

The paper shows that PRC2 represses genes during sexual development in Neurospora crassa, and its loss leads to premature fruiting body formation.

The paper analyzes the genetic structure of a Sindhi population in West coast India, finding significant genetic affinity with the Burusho group and evidence of recent admixture with the Konkani population.

This study identifies HDA-1 as essential for maintaining epigenome stability in Neurospora crassa by regulating H3K27me3 and heterochromatin integrity.

SAFE-LD estimates linkage disequilibrium from GWAS summary statistics using pseudo-genotypes that preserve in-sample LD while protecting privacy.

The paper identifies effective promoters for CRISPR editing in Anopheles sinensis, achieving high editing efficiency in transgenic mosquitoes.

The paper systematically assesses the functional impact of all TUBA1A missense variants using experimental and computational methods, improving clinical variant classification.

This study identifies vitamin B12 as a suppressor of Verheij syndrome-like defects in a C. elegans PUF60 model by restoring metabolic balance and splicing.

This paper introduces RoP, a method to analyze phase effects in genetic association studies using long-read sequencing data, showing improved detection of cis and trans effects in cystic fibrosis loci.

The paper uses single-cell RNA-seq to show no evidence of meiotic sex chromosome inactivation in threespine stickleback fish, suggesting MSCI is not conserved in teleosts.

The paper examines linkage disequilibrium patterns in chicken QTLRs for Mareks Disease, finding chaotic LD structures that challenge GWAS interpretation.

This paper introduces an integrated genomic mating strategy that combines optimal recycling with genomic mating to enhance genetic diversity and gain efficiency in breeding programs.

The paper models TE dynamics in genomes under asexual reproduction, showing TE persistence depends on genome diversity and TE silencing mechanisms.

This study identifies genetic associations between brain structure/function, cognitive traits, and psychopathologies in children using polygenic scores and multivariate analysis.

The paper proposes a method to correct for multiple testing in genome scans for recent positive selection using identity-by-descent segments, showing it controls FWER and detects selection signals across ancestry groups.