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The paper uses sequence-to-function models to show that long-range regulatory information in vertebrate genomes stops being shared before local sequence information, with a phylogenetic boundary around 320-435 Mya.

This study investigates whether pupil size reflects physical effort or motor fatigability during sustained repetitive movement and finds that it reflects effort but not fatigability.

The paper investigates how object identity is affected by motion at saccadic speeds during eye movements, finding that object features survive but their link to specific objects is lost.

PhyMorphS generates realistic white matter microstructures using physics-guided mesh growth, reproducing key morphological features and enabling dMRI signal studies.

This study investigates how ADHD affects exploration-exploitation trade-offs using a bandit task and EEG, finding heightened recent reward reliance and midfrontal sensitivity to outcome differences in ADHD without performance deficits.

This study maps viral RNA signals across cell types and tissues in colorectal cancer, identifying significant viral associations with specific cell types and tissue conditions.

The paper derives a scaling law for biological learning by linking inductive bias to learning speed and validates it using human and mouse datasets.

This study analyzes the genetic context of antimicrobial resistance genes in river sediments using metagenomics to identify mobile elements and host associations.

This paper introduces a family of dissimilarity measures for phylogenetic networks that better capture reticulation differences than existing methods.

This study investigates how the auditory system tracks moving sound sources by integrating velocity and spatial error in a delayed frame, showing improved prediction with preceding head orientation.

This study designs gene regulatory networks to slow somatic evolution in simplified multicellular organisms and identifies tradeoffs between network robustness and fitness.

The paper develops a computational model to simulate the self-assembly of cortical microcircuits from progenitors, reproducing experimentally measured connectivity without prescribing individual connections.

The paper develops a computational model to explain how mechanical stimuli drive the formation of perinuclear actin structures through mechanosensitive actin polymerization.

This study shows that C9orf72 repeat expansions cause presymptomatic lysosomal dysfunction in Drosophila, leading to DPR secretion and neurotoxicity, which can be mitigated by valproic acid.

The paper uses whole-brain MRSI to construct metabolic connectomes in psychosis risk individuals, finding altered network organization and gradient coherence compared to healthy controls.

DaliScope analyzes DALI structural alignments to uncover protein relationships and structural patterns, revealing unannotated domains and structurally anchored sequence signatures.

This study profiles SCN transcriptomes in soybean roots under single or combined SBA infestations, finding increased SCN gene expression in resistant cultivars under combined treatment.

NeuroDisco provides optogenetic stimulation to neuronal cultures to reduce synchronized bursting and enable functional analysis of neuronal activity.