Roman Bauer

Computational model of developmental self-assembly of a cortical microcircuit

The paper develops a computational model to simulate the self-assembly of cortical microcircuits from progenitors, reproducing experimentally measured connectivity without prescribing individual connections.

Open Benchmarking for Cell-Based Multiscale Models: Lessons from a Community Initiative

This paper presents a community-driven benchmarking initiative for cell-based multiscale models, highlighting variations in tool implementations and advocating for standardized benchmarks and interoperability.

Retinal waves in adaptive rewiring networks orchestrate convergence and divergence in the visual system

The paper shows retinal waves drive the formation of divergent hubs and convergence in neural networks through adaptive rewiring.

Retinal self-organization: a model of RGC and SAC mosaic formation

This paper develops a computational model to study retinal mosaic formation, finding that cell migration yields the most regular mosaics and that SAC populations in GCL and INL may not be independent.

BioDynaMo: a general platform for scalable agent-based simulation

BioDynaMo is a scalable agent-based simulation platform that outperforms existing tools by three orders of magnitude, enabling large-scale simulations in neuroscience, oncology, and epidemiology.

Creative destruction: a basic computational model of cortical layer formation

The paper presents a computational model of cortical layer formation that incorporates apoptosis and gene regulatory dynamics to explain normal and pathological development.

A Generative Growth Model for Thalamocortical Axonal Branching in Primary Visual Cortex

The paper introduces a generative model for axonal branching in the primary visual cortex that outperforms existing models in statistical accuracy and biological plausibility.