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This study shows that vitamin B5 enhances intestinal neuropeptide secretion in C. elegans, improving antioxidant response through specific cellular mechanisms.

This study uses HaloPROTAC-mediated SOX10 degradation in melanoma cells to identify novel target genes and reveal SOX10's role in drug resistance and metastasis.

This study creates a fast neutron mutant library in Ipomoea purpurea, showing dose-dependent phenotypic and genetic variation in ecologically relevant traits.

This study compares microrobot and cellbot locomotion on synthetic substrates and cardiac tissue, showing how surface interactions and magnetic fields affect movement speed and direction.

The paper introduces DARTs, a platform for programmable cell targeting using antibody-conjugated nanoparticles, identifying new surface antigens for gene editing in neural cells.

The paper uses single-cell RNA sequencing to analyze immune cell interactions in asymptomatic and symptomatic malaria patients, finding reduced monocyte-T cell interactions and increased inflammation in symptomatic cases.

This study uses untargeted metabolomics to show that the red alga Halymenia floresii selectively enriches lipid-associated metabolites at its surface for chemical defense against microbial colonization.

multiomeR provides a reproducible R pipeline for analyzing large-scale single-nucleus Epi Multiome datasets, improving efficiency and reducing memory usage compared to existing workflows.

This study identifies a nucleolar role for Drosophila Argonaute 1, showing it associates with snoRNP machinery and regulates pre-rRNA levels and cell growth.

GlyEnzEA constructs enzyme-specific glycan sets from glycomics data and identifies significant changes in specific enzyme groups.

This paper introduces a statistical meta-aggregation method for EEG classification in Parkinson's disease, improving subject-level classification performance by aggregating epoch-wise predictions more effectively.

The paper shows that larval quality, not supply, drives barnacle recruitment by influencing habitat selection and settlement success.

This study shows that inflammation triggers POLE-mutant colorectal cancer in mice, revealing inflammation as a key driver and establishing a preclinical model for drug discovery.

This paper presents a rapid, automation-friendly pipeline for characterizing de novo protein binders without cell culture or purification, achieving binding affinity and kinetics in three days.

This paper generates a time-resolved proteome and phosphoproteome dataset of Y1 adrenocortical cells under FGF2 stimulation and SOS inhibition, revealing 14,512 phosphosites and 8,919 protein groups with significant changes.

This paper introduces a Rheo-NMR platform to analyze amyloid formation kinetics in real-time and provides insights into environment-dependent aggregation pathways.

The paper creates a pan-cancer catalog of mutation patterns at transcription factor binding sites across 15 tissue types, revealing enrichment in nearly one third of TF-binding site pairs.