Multivariate genetic analysis maps shared biology between psoriasis and cardiovascular diseases
Charalabos Antonatos, Eleftheria Georgalaki, Ioanna Tzoulaki, Yiannis Vasilopoulos
Author
University of IoanninaORCID 0000-0002-4275-9328Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
8 papers
Recent·Most cited
Charalabos Antonatos, Eleftheria Georgalaki, Ioanna Tzoulaki, Yiannis Vasilopoulos
James Yarmolinsky, Francesca R Cavallo, Fotios Koskeridis…·Ioanna Tzoulaki
This paper identifies shared genetic loci between inflammation and cancer risk using non-causal associations, revealing potential therapeutic targets.
Devendra Meena, Christos V. Chalitsios, Jingxian Huang…·Ioanna Tzoulaki
Felix O’Farrell, Benjamin Aleyakpo, Rima Mustafa…·Raha Pazoki
The paper investigates the role of WDPCP in alcohol consumption, lipid metabolism, and liver cirrhosis using human and model organism studies.
Vasiliki Lagou, Longda Jiang, Anna Ulrich…·Inga Prokopenko
This study performs a GWAS on random glucose measurements in 493,036 individuals, identifying 128 loci associated with glycaemic traits and providing insights into diabetes biology and treatment.
Dipender Gill, Marios K. Georgakis, Fotios Koskeridis…·Ioanna Tzoulaki
The paper uses genetic variants to investigate side effects and repurposing potential of antihypertensive drugs, finding a link between calcium channel blockers and increased diverticulosis risk.
Εvangelos Εvangelou, He Gao, Congying Chu…·Paul Elliott
This study identifies 46 novel genetic loci associated with alcohol consumption and suggests shared genetic mechanisms with neuropsychiatric disorders using GWAS and functional analyses.
Michael Inouye, Gad Abraham, Christopher P. Nelson…·Nilesh J. Samani
This paper develops a genomic risk score for coronary artery disease using 1.7 million variants and tests it in UK Biobank, showing it outperforms conventional risk factors in predicting CAD risk.