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MIEN improves glycan pose ranking by distinguishing experimentally observed conformations from non-native ones in protein-carbohydrate interactions.

This study investigates how PV and SOM interneurons respond to different microstimulation patterns and how their activation dynamics influence cortical network activity and adaptation.

The paper identifies a non-catalytic repressor function of TET1 and an activating role of macroH2A.2 in bivalent chromatin during neuroectoderm differentiation.

This paper demonstrates that a magnetic field modulates the formation of a covalent photoadduct in AsLOV2, enhancing signaling through spin-selective radical-pair reactions.

This study uses hidden Markov modeling to analyze dynamic functional connectivity in MS patients, finding altered state occupancy and transitions associated with disability and cognition.

This study identifies factors governing cysteine detection in chemoproteomics using machine learning and statistical filtering, showing that peptide properties and abundance are key determinants.

The paper identifies innate immune activation and CMV-specific antibody reactivity as early markers of preclinical NMOSD, preceding clinical onset by over 12 years.

The paper examines how coastal fog exposure affects epiphytic cryptogam communities and finds little variation in abundance, reproduction, and community composition despite strong microclimate differences.

This study identifies Dynamin-2 as the fission factor for SNX1-coated endosomal tubules, showing it is required for tubule scission and cargo recycling.

This paper introduces an improved SS-vis-OCT system with extended imaging depth and sensitivity for biological samples.

This study conducts the first genome-wide association study of the phosphoproteome, identifying genetic variants influencing protein phosphorylation and linking them to disease traits.

This paper presents a protocol to identify and rank species needing urgent management action for Target 4 of the Global Biodiversity Framework using IUCN Red List data.

The paper investigates intracellular mechanical properties and structural organization in RPE1 cells, finding no significant spatial mechanical patterns or correlations between structures and mechanical properties.

This study identifies and reconstitutes the biosynthetic pathway for Securinega alkaloids in Flueggea suffruticosa, revealing a connection to cyanogenic glucoside biosynthesis.

The paper identifies a distributed architectural code involving cytoskeletal, membrane, and lipid regulators that governs nuclear reshaping during DNA repair.

The paper identifies HPV-associated premalignant lesions in tonsils and suggests oral HR-HPV mRNA as a potential biomarker for early detection.

The paper audits a benchmarking framework for single-cell perturbation models, revealing flaws in metric interpretation and calibration, and identifies a specific calibration failure in split-conformal prediction.

This study examines genomic diversity in South American lowland maize landraces from Uruguay and Brazil, finding geographic patterns in genome size, heterochromatic knobs, and repetitive sequences.

This study finds that sickness-like depressive symptoms in breast cancer survivors are more strongly linked to proinflammatory gene expression and myeloid cell abundance than negative affect symptoms.

The paper shows that the m6A writer spares canonical 3' splice sites from methylation, allowing efficient splicing despite cotranscriptional methylation.