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This study shows PHC2-dependent PRC1 assemblies stabilize Hox gene boundaries and motor neuron identities during development.

This study examines how fetal activity patterns in utero relate to postnatal infant sleep behavior, finding that fetal circadian entrainment predicts infant sleep preferences.

This study identifies circEPSTI1 as a regulator of dengue infection through a miR-942-5p-SERPINE1-AKT1 signaling axis and shows that Tiplaxtinin suppresses this pathway to inhibit DENV replication.

This study identifies early innate immune signatures following Ad26.COV2.S vaccination that correlate with vaccine durability and protective efficacy in rhesus macaques and humans.

The paper resolves a 245-year-old taxonomic confusion between Ganoderma lingzhi and G. lucidum using a historical specimen and genomic analysis, showing they diverged over 12 million years ago.

This study shows that the lack of ancestral SARS-CoV-2 immune imprinting in children makes them more susceptible to BA.3.2.2 infection, as it evades neutralizing antibodies typically present in adults.

This study examines how varying virtual visual stimulus amplitudes affect standing postural responses in VR, finding that higher amplitudes increase oscillation and decrease gain, suggesting nonlinear control.

This study shows that type I interferon signaling is critical for early control of Borrelia burgdorferi infection by enhancing macrophage function and immune cell recruitment, but contributes to inflammation later in infection.

This paper compares OncoPro™ and Wnt-based media in patient-derived tumor organoids, finding distinct phenotypic, transcriptomic, and pharmacologic differences.

This study shows that intermediate temporal resolution captures higher-order neural dependencies and efficient information representation better than coarse or fine resolutions.

This study identifies an essential follower peptide for triculamin biosynthesis and shows its role in enzyme-substrate complex formation and substrate promiscuity.

Zapit provides an open-source platform for random-access laser-scanning optogenetics in mice, enabling user-friendly and accessible experiments.

This study co-cultures yeast and plant cells to generate consortia factors with a distinct metabolome enriched in antioxidants, showing stronger antioxidant activity than individual cultures.

The paper presents a chromosome-level, haplotype-resolved genome assembly for the European moose, achieving high completeness and gene annotation.

This study uses tFUS to show that stimulating the central thalamus impairs vigilance and the pulvinar affects visuospatial attention in healthy volunteers.

This study evaluates irinotecan's effects on intestinal motility, permeability, and histopathology in rats and Caco-2 cells, finding increased motility, permeability, and tissue damage.

This study shows that cells decode calcium oscillation frequency through a multi-kinase network that regulates transcription via NF-κB and MYC.

This paper develops an open-source biopotential recording system with performance comparable to high-end devices, validated through in-vivo and benchtop experiments.

This study identifies HIPK2 and IKKβ as kinases that phosphorylate TAp63α, stabilizing it during the oocyte DNA damage response and enhancing oocyte survival.