Elizabeth A White

Behavioral effects of targeting the central thalamus and pulvinar with transcranial ultrasound stimulation in healthy volunteers

This study uses tFUS to show that stimulating the central thalamus impairs vigilance and the pulvinar affects visuospatial attention in healthy volunteers.

Inactivation of the RB1 and PTPN14 tumor suppressors cooperatively enables the lifespan extension activity of the human papillomavirus E7 oncoprotein

This study shows that high-risk HPV E7 proteins require inactivating both RB1 and PTPN14 to extend keratinocyte lifespan, while low-risk E7 needs PTPN14 inactivation alone.

HPV18 E7 inhibits LATS1 kinase and activates YAP1 by degrading PTPN14

This study shows HPV18 E7 degrades PTPN14, inhibits LATS1 kinase, and activates YAP1, which inhibits keratinocyte differentiation.

Human papillomavirus 16 E2 regulates keratinocyte gene expression relevant to cancer and the viral life cycle

This study shows HPV16 E2 regulates host gene expression in keratinocytes, overlaps with genome-wide effects of HPV16, and correlates with clinical outcomes in head and neck cancers.