Author

A. A. Aleksandrov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:non-human primate· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

L. He· 2 shared A. S. Kennedy· 1 shared D. Cholon· 1 shared D. M. Cyr· 1 shared D. S. Gingerich· 1 shared H. Y. Ren· 1 shared J. F. Fay· 1 shared J. N. Kousouros· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

L. He

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Author profile →

2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 28, 2020

DNAJB12 and Hsp70 Facilitate the Conformation Specific Degradation of Arrested N1303K-CFTR Intermediates by ERQC-Autophagy

L. He, A. S. Kennedy, S. Houck…·D. M. Cyr

This study shows DNAJB12 and Hsp70 facilitate conformation-specific degradation of N1303K-CFTR intermediates via ERQC-autophagy, distinct from ERAD.

DOI 10.1101/2020.10.28.358580

humanproteomics

𝕏 PostBluesky

BiophysicsbioRxivMar 2, 2018

Cryo-EM visualization of an active high open probability CFTR ion channel

J. F. Fay, L. A. Aleksandrov, T. J. Jensen…·J. Z. Chen

The paper determines the structure of active and inactive states of a thermostabilized CFTR channel using cryo-EM, revealing structural changes related to channel function.

DOI 10.1021/acs.biochem.8b00763

𝕏 PostBluesky