Author

A. A. Brockman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

R. A. Ihrie· 2 shared A. Chakrabarty· 1 shared A. Filby· 1 shared A. Gusnanto· 1 shared A. Ismail· 1 shared A. M. Mistry· 1 shared B. C. Mobley· 1 shared B. Hunter· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

R. A. Ihrie

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2 papers

Recent·Most cited

IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma

S. Medina, A. A. Brockman, C. E. Cross, M. J. Hayes, B. C. Mobley, A. M. Mistry, S. Chotai, K. D. Weaver, R. Thompson, L. B. Chambless, R. A. Ihrie, J. M. Irish

This study identifies IL-8 as a key factor instructing macrophage identity in glioblastoma, showing IL-8 is necessary for generating CD32+ M_IL-8 macrophages in tumors contacting the lateral ventricle.

bioRxiv · Mar 29, 2024 · PreprintCancer Biology

GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data

S. A. Ajaib, D. Lodha, S. Pollock, G. Hemmings, M. Finetti, A. Gusnanto, A. Chakrabarty, A. Ismail, E. Wilson, F. S. Varn, B. Hunter, A. Filby, A. A. Brockman, D. McDonald, R. Verhaak, , L. F. Stead

This paper develops GBMdeconvoluteR, a tool to accurately infer neoplastic and immune cell proportions in bulk glioblastoma RNAseq data, validated against imaging mass cytometry.

Neuro-Oncology · Jul 6, 2023Peer-reviewedCancer Biology