Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
S. Medina, A. A. Brockman, C. E. Cross, M. J. Hayes, B. C. Mobley, A. M. Mistry, S. Chotai, K. D. Weaver, R. Thompson, L. B. Chambless, R. A. Ihrie, J. M. Irish
This study identifies IL-8 as a key factor instructing macrophage identity in glioblastoma, showing IL-8 is necessary for generating CD32+ M_IL-8 macrophages in tumors contacting the lateral ventricle.
bioRxiv · Mar 29, 2024 · PreprintCancer Biology
A. K. von Lersner, F. C. L. Fernandes, P. M. M. Ozawa, T. Vagner, S. M. Lima, B. H. Sung, M. Wehbe, K. Franze, J. T. Wilson, J. M. Irish, A. Weaver, D. Di Vizio, A. Zijlstra
EV Fingerprinting uses flow cytometry to resolve EV heterogeneity and detect tumor-derived EVs in plasma.
bioRxiv · Nov 10, 2022 · PreprintCell Biology
T. Bartkowiak, S. M. Lima, M. J. Hayes, A. M. Mistry, J. Sinnaeve, N. Leelatian, C. E. Roe, B. C. Mobley, K. D. Weaver, R. C. Thompson, L. B. Chambless, R. A. Ihrie, J. M. Irish
This study shows that glioblastomas contacting the lateral ventricle have distinct immune features, including elevated T cell checkpoint receptors and suppressive myeloid cells, suggesting new therapeutic targets.
bioRxiv · Feb 16, 2022 · PreprintImmunology
S. Kaviany, T. Bartkowiak, D. E. Dulek, Y. W. Khan, M. J. Hayes, S. K. Schaefer, D. O. Dahunsi, J. A. Connelly, J. M. Irish, J. C. Rathmell
This study identifies how STAT1 gain-of-function variants alter T cell prevalence, metabolism, and IL-6 sensitivity in patients, revealing their role in immune dysregulation.
bioRxiv · Nov 10, 2021 · PreprintImmunology
K. J. Kramer, E. M. Wilfong, K. Voss, S. Barone, A. R. Shiakolas, N. Raju, C. E. Roe, N. Suryadevara, L. M. Walker, S. C. Wall, A. Paulo, S. Schaefer, D. Dahunsi, C. S. Westlake, J. E. Crowe, , J. M. Irish
bioRxiv · Jul 28, 2021Immunology
S. Le Gallou, F. Lhomme, J. M. Irish, A. Mingam, C. Pangault, C. Monvoisin, J. Ferrant, I. Azzaoui, D. Rossille, K. Bouabdallah, G. Damaj, G. Cartron, P. Godemer, S. Le Gouill, O. Casanovas, , M. Roussel
The paper assesses monocyte subsets in DLBCL patients, finding that nonclassical monocytes are decreased in peripheral blood and prone to migrate into tumors, correlating with adverse outcomes.
bioRxiv · Apr 10, 2021Immunology
A. Meghraoui-Kheddar, B. G. Chousterman, N. Guillou, S. M. Barone, S. Granjeaud, H. Vallet, A. Corneau, K. Guessous, A. Boissonnas, J. M. Irish, C. Combadiere
The paper identifies two new immature and dysfunctional neutrophil subsets that serve as an early blood signature for sepsis, detectable by routine flow cytometry.
bioRxiv · May 29, 2020 · PreprintImmunology
N. Leelatian, J. Sinnaeve, A. M. Mistry, S. M. Barone, K. E. Diggins, A. R. Greenplate, K. D. Weaver, R. C. Thompson, L. B. Chambless, B. C. Mobley, R. A. Ihrie, J. M. Irish
This paper introduces RAPID, an unsupervised machine learning algorithm that identifies single cell phenotypes and assesses clinical risk stratification in glioblastoma patients using single cell mass cytometry data.
bioRxiv · Jun 1, 2019Cancer Biology