A. Alexandrescu

Formerly degenerate seventh zinc finger domain from transcription factor ZNF711 rehabilitated by experimental NMR structure

The paper shows that a previously thought non-functional zinc finger domain from ZNF711 can fold with three metal ligands and is catalytically active.

Structure-Activity Relationships in the Design of Mitochondria-Targeted Peptide Therapeutics

This study analyzes structure-activity relationships of mitochondria-targeted tetrapeptides, finding that side chain composition and sequence register significantly affect their efficacy and membrane interactions.

NMR Mapping of Disordered Segments from a Viral Scaffolding Protein Encapsulated in a 23 MDa Procapsid Complex

This paper uses NMR to identify mobile segments of the phage P22 scaffolding protein in solution and within a procapsid complex, revealing the N-terminus remains disordered and negatively charged when bound.

The phage L capsid decoration protein has a novel OB-fold and an unusual capsid binding strategy

The paper determines the structure of the phage L Dec protein and its binding strategy to the capsid using cryo-EM and NMR.