Author

J. R. Schrad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

K. N. Parent· 3 shared A. Alexandrescu· 1 shared A. M. Tayar· 1 shared C. M. Teschke· 1 shared D. Nicastro· 1 shared E. B. Gilcrease· 1 shared E. V. Pavlov· 1 shared G. Fu· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersBiophysics

K. N. Parent

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cryo-electron tomography of eel sperm flagella reveals a molecular "minimum system" for motile cilia

J. R. Schrad, G. Fu, W. E. Hable, A. M. Tayar, K. Oliveira, D. Nicastro

This study uses cryo-electron tomography to analyze the structure of eel sperm flagella, revealing a minimal system with retained remnants of regulatory complexes and unique structural features.

bioRxiv · Jul 16, 2023Cell Biology

The Mitochondrial Permeability Transition Phenomenon Elucidated by Cryo-EM Reveals the Genuine Impact of Calcium Overload on Mitochondrial Structure and Function

J. O. Strubbe, J. R. Schrad, E. V. Pavlov, J. F. Conway, K. N. Parent, J. N. Bazil

The study uses cryo-EM to show how calcium overload causes mitochondrial permeability transition by forming calcium phosphate granules and inner membrane fragmentation, and reveals cyclosporin A's role in preserving inner membrane structure.

Scientific Reports · Jan 13, 2021Peer-reviewedCell Biology

Boiling Acid Mimics Intracellular Giant Virus Genome Release

J. R. Schrad, J. S. Abrahao, J. R. Cortines, K. N. Parent

This study identifies conserved molecular forces triggering giant virus genome release and identifies specific proteins released during infection.

bioRxiv · Sep 20, 2019 · PreprintBiophysics

The phage L capsid decoration protein has a novel OB-fold and an unusual capsid binding strategy

R. L. Newcomer, J. R. Schrad, E. B. Gilcrease, S. R. Casjens, M. Feig, C. M. Teschke, A. Alexandrescu, K. N. Parent

The paper determines the structure of the phage L Dec protein and its binding strategy to the capsid using cryo-EM and NMR.

bioRxiv · Feb 1, 2019Biophysics