Author

A. Alfranca

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

I. Santos· 3 shared M. J. Buzon· 3 shared C. Delgado-Arevalo· 2 shared E. Martin-Gayo· 2 shared F. Sanchez-Madrid· 2 shared I. Sanchez-Cerrillo· 2 shared I. Tsukalov· 2 shared J. Sanz· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

I. Santos

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Combined Dendritic Cell And Anti-TIGIT Immunotherapy Potentiate Trail+ Memory NK Cells Against HIV-1 Infected Cells

I. S. Cerrillo, O. Popova, M. A. Lera, I. Tsukalov, M. C. Mirabent, I. Santos, L. G. Fraile, P. Fuentes, C. D. Arevalo, J. Alcain, N. S. Gaona, M. L. Diez, C. M. Calleja, A. Alfranca, M. Genesca, , E. Martin-Gayo

Combining dendritic cell stimulation with anti-TIGIT antibodies enhances memory NK cell cytotoxicity against HIV-1 infected CD4+ T cells in vitro and in vivo.

bioRxiv · Apr 9, 2024 · PreprintImmunology

ART duration and immunometabolic state determine efficacy of DC-based treatment restoring functional HIV- specific CD8+ T cells in PLWH.

M. Calvet-Mirabent, I. Sanchez-Cerrillo, N. Martin-Cofreces, H. De La Fuente, I. Tsukalov, C. Delgado-Arevalo, M. J. Calzada, I. Santos, J. Sanz, L. Garcia-Fraile, F. Sanchez-Madrid, A. Alfranca, M. A. Munoz-Fernandez, M. J. Buzon, E. M.-G. Martin-Gayo

This study shows that ART duration affects CD8+ T cell function in HIV-1 patients, with longer ART improving DC-based immunotherapy outcomes through specific immunometabolic changes.

bioRxiv · Jan 14, 2022 · PreprintImmunology

TAILORED DC INDUCE PROTECTIVE HIV-1 SPECIFIC POLYFUNCTIONAL CD8+ T CELLS IN THE LYMPHOID TISSUE FROM HUMANIZED BLT MICE

M. Calvet-Mirabent, D. T. Claiborne, M. Deruaz, S. Tanno, C. Serra, C. Delgado-Arevalo, I. Sanchez-Cerrillo, I. Santos, J. Sanz, L. Garcia-Fraile, F. Sanchez-Madrid, A. Alfranca, M. A. Munoz-Fernandez, T. M. Allen, M. J. Buzon, , E. Martin-Gayo

This study shows that TBK1-primed dendritic cells reduce HIV-1 disease progression in humanized mice by enhancing CD8+ T cell responses.

bioRxiv · Jun 30, 2021 · PreprintImmunology