Author

L. Garcia-Fraile

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Alfranca· 2 shared C. Delgado-Arevalo· 2 shared F. Sanchez-Madrid· 2 shared I. Sanchez-Cerrillo· 2 shared I. Santos· 2 shared J. Sanz· 2 shared M. A. Munoz-Fernandez· 2 shared M. Calvet-Mirabent· 2 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. Alfranca

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ART duration and immunometabolic state determine efficacy of DC-based treatment restoring functional HIV- specific CD8+ T cells in PLWH.

M. Calvet-Mirabent, I. Sanchez-Cerrillo, N. Martin-Cofreces, H. De La Fuente, I. Tsukalov, C. Delgado-Arevalo, M. J. Calzada, I. Santos, J. Sanz, L. Garcia-Fraile, F. Sanchez-Madrid, A. Alfranca, M. A. Munoz-Fernandez, M. J. Buzon, E. M.-G. Martin-Gayo

This study shows that ART duration affects CD8+ T cell function in HIV-1 patients, with longer ART improving DC-based immunotherapy outcomes through specific immunometabolic changes.

bioRxiv · Jan 14, 2022 · PreprintImmunology

TAILORED DC INDUCE PROTECTIVE HIV-1 SPECIFIC POLYFUNCTIONAL CD8+ T CELLS IN THE LYMPHOID TISSUE FROM HUMANIZED BLT MICE

M. Calvet-Mirabent, D. T. Claiborne, M. Deruaz, S. Tanno, C. Serra, C. Delgado-Arevalo, I. Sanchez-Cerrillo, I. Santos, J. Sanz, L. Garcia-Fraile, F. Sanchez-Madrid, A. Alfranca, M. A. Munoz-Fernandez, T. M. Allen, M. J. Buzon, , E. Martin-Gayo

This study shows that TBK1-primed dendritic cells reduce HIV-1 disease progression in humanized mice by enhancing CD8+ T cell responses.

bioRxiv · Jun 30, 2021 · PreprintImmunology