Author

A. B. Shaik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. H. Williams· 1 shared J. L. Meier· 1 shared K. F. Suazo· 1 shared M. C. Crawford· 1 shared M. S. Penikalapati· 1 shared R. E. Swenson· 1 shared T. Andresson· 1 shared X. Chen· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

J. H. Williams

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1 paper

Recent·Most cited

Paralogue-selective degradation of the lysine acetyltransferase EP300

X. Chen, M. C. Crawford, Y. Xiong, A. B. Shaik, K. F. Suazo, M. S. Penikalapati, J. H. Williams, T. Andresson, R. E. Swenson, J. L. Meier

This study develops a small molecule, MC-1, that selectively degrades EP300 over CREBBP, revealing factors governing paralogue-specific degradation and its impact on cancer cell proliferation.

bioRxiv · May 3, 2024Biochemistry