License to cut: Smart RNA guides for conditional control of CRISPR-Cas9
A. Baccouche, A. Adel, N. Yachie, T. Fujii, A. J. Genot
This paper introduces smart RNA guides that conditionally activate CRISPR-Cas9 in response to specific RNA openers, demonstrating flexibility with miRNA and Boolean logic circuits in mammalian cells.
bioRxiv · Oct 26, 2022 · PreprintBioengineering