Macrophages control pathological interferon responses during viral respiratory infection
D. A. Hoagland, P. Rodriguez-Morales, A. O. Mann, S. Yu, A. Lai, A. Baez Vazquez, S. D. Pope, J. Lim, S. Li, X. Zhang, M. O. Li, R. Medzhitov, R. A. Franklin
This study identifies macrophage-derived Oncostatin M as a critical regulator of type I interferon responses during viral respiratory infection, preventing excessive inflammation.
bioRxiv · Dec 16, 2023Immunology