Author

M. O. Li

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

X. Zhang· 2 shared A. Baez Vazquez· 1 shared A. E. Cornish· 1 shared A. Lai· 1 shared A. O. Mann· 1 shared A. Tan· 1 shared C. Edwards· 1 shared C. M. Rice· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

X. Zhang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Onco-Circuit Addiction and Onco-Nutrient mTORC1 Signaling Vulnerability in a Model of Aggressive T Cell Malignancy

X. Wang, A. E. Cornish, M. H. Do, J. S. Brunner, T.-W. Hsu, Z. Xu, I. Malik, C. Edwards, K. J. Capistrano, X. Zhang, M. H. Ginsberg, L. W. S. Finley, M. S. Lim, S. M. Horwitz, M. O. Li

The paper shows that mTORC1 signaling hypersensitivity to leucine drives an onco-circuit in T cell malignancy, and a low leucine diet is therapeutic without impairing T cell immunity.

bioRxiv · Apr 3, 2024 · PreprintCancer Biology

Macrophages control pathological interferon responses during viral respiratory infection

D. A. Hoagland, P. Rodriguez-Morales, A. O. Mann, S. Yu, A. Lai, A. Baez Vazquez, S. D. Pope, J. Lim, S. Li, X. Zhang, M. O. Li, R. Medzhitov, R. A. Franklin

This study identifies macrophage-derived Oncostatin M as a critical regulator of type I interferon responses during viral respiratory infection, preventing excessive inflammation.

bioRxiv · Dec 16, 2023Immunology

Innate-adaptive IFN cross-talk reprograms myeloid and T cells for antitumor immunity with a second-generation recombinant MVA

S. Liu, Y. Wang, G. Mazo, S. Baseer Tariq, J. Angulo-Lozano, N. Yang, T. Zhang, Y. Wang, D. Hirschhorn, L. Ji, A. Tan, J. Wang, W. Yan, J. Choi, J. Z. Xiang, , L. Deng

This paper describes a second-generation recombinant MVA vaccine that enhances antitumor immunity by reprogramming myeloid and T cells through innate-adaptive IFN cross-talk.

bioRxiv · Sep 25, 2022 · PreprintImmunology