Author

S. D. Pope

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

R. Medzhitov· 3 shared M. L. Meizlish· 2 shared R. A. Franklin· 2 shared S. Li· 2 shared A. B. Chang· 1 shared A. Baez Vazquez· 1 shared A. E. Daly· 1 shared A. Gonzalez· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersImmunology

R. Medzhitov

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Author profile →

5 papers

Recent·Most cited

Stepwise neofunctionalization of the NF-κB family member c-Rel during vertebrate evolution

A. E. Daly, A. B. Chang, P. Purbey, K. J. Williams, G. Yeh, S. Li, S. D. Pope, B. Venkatesh, B. D. Redelings, S. Li, K. Nguyen, J. Rodriguez, K. Jorgensen, T. Siggers, L. Chen, S. T. Smale

The paper shows c-Rel, an NF-κB family member, evolved unique DNA-binding properties in mammals, enhancing its ability to regulate Il12b and support immune complexity.

Nature Immunology · Apr 30, 2025Peer-reviewedImmunology

Macrophages control pathological interferon responses during viral respiratory infection

D. A. Hoagland, P. Rodriguez-Morales, A. O. Mann, S. Yu, A. Lai, A. Baez Vazquez, S. D. Pope, J. Lim, S. Li, X. Zhang, M. O. Li, R. Medzhitov, R. A. Franklin

This study identifies macrophage-derived Oncostatin M as a critical regulator of type I interferon responses during viral respiratory infection, preventing excessive inflammation.

bioRxiv · Dec 16, 2023Immunology

Macrophages sense ECM mechanics and growth factor availability through cytoskeletal remodeling to regulate their tissue repair program

M. L. Meizlish, Y. Kimura, S. D. Pope, R. Matta, C. Kim, N. Philip, L. Meyaard, A. Gonzalez, R. Medzhitov

bioRxiv · Jun 28, 2023 · PreprintImmunology

Microenvironmental sensing by fibroblasts controls macrophage population size

X. Zhou, R. A. Franklin, M. Adler, T. S. Carter, E. Condiff, T. S. Adams, S. D. Pope, N. H. Philip, M. L. Meizlish, N. S. Kaminski, R. Medzhitov

This study shows fibroblasts sense space and regulate macrophage numbers via growth factor production.

bioRxiv · Jan 18, 2022Immunology

The lupus susceptibility locus Sgp3 encodes the suppressor of endogenous retrovirus expression SNERV

R. S. Treger, S. D. Pope, Y. Kong, M. Tokuyama, M. Taura, A. Iwasaki

This study identifies SNERV, a suppressor of endogenous retrovirus expression, as a lupus susceptibility gene, showing its role in preventing ERV overexpression and associated nephritis.

bioRxiv · Dec 4, 2018Immunology