A. Black

An off-lattice discrete model to characterise filamentous yeast colony morphology

The paper uses an off-lattice agent-based model and experimental data to show that budding mechanisms and nutrient concentration drive filamentous yeast colony morphology.

Improved determination of protein turnover rate with heavy water labeling by mass isotopomer ratio selection

This paper introduces a method to improve protein turnover rate calculation using heavy water labeling and mass spectrometry, increasing coverage of well-fitted peptides by 25-82% in mouse organ proteomes.

Tissue Usage Preference and Intrinsically Disordered Region Remodeling of Alternative Splicing Derived Proteoforms in the Heart

The paper analyzes mass spectrometry data to identify alternative splicing-derived protein variants in human heart chambers, finding tissue-specific isoforms and their functional implications in protein binding.

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent NF-κB inflammatory response

This study shows that mitochondrial outer membrane permeabilization triggers ubiquitin-dependent NF-κB inflammation by recruiting NEMO to ubiquitylated mitochondria.

The Effect of Bottleneck Size on Evolution in Nested Darwinian Populations

This paper investigates how varying bottleneck sizes in nested Darwinian populations affect evolutionary dynamics, showing that larger bottlenecks can reverse evolutionary direction under certain conditions.

Actin remodelling controls proteasome homeostasis upon stress

The paper shows that actin remodelling facilitates RPAC translation under stress, maintaining proteasome homeostasis in yeast.