Author

A. Blackstone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

A. C. Walls· 3 shared B. Fiala· 3 shared E. Kepl· 3 shared L. Carter· 3 shared M. Johnson· 3 shared M. N. Pham· 3 shared N. Brunette· 3 shared N. P. King· 3 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. C. Walls

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Author profile →

3 papers

Recent·Most cited

Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice

A. C. Walls, L. A. VanBlargan, K. Wu, A. Choi, M. J. Navarro, D. Lee, L. Avena, D. M. Berrueta, M. N. Pham, S. Elbashir, M. C. Miranda, E. Kepl, M. Johnson, A. Blackstone, K. R. Sprouse, , D. Veesler

This study compares neutralizing antibody responses to SARS-CoV-2 variants in vaccinated humans and mice, finding that mice do not accurately reflect the breadth and potency seen in humans.

bioRxiv · Feb 7, 2022Immunology

Stabilization of the SARS-CoV-2 Spike receptor-binding domain using deep mutational scanning and structure-based design

D. Ellis, N. Brunette, K. H. D. Crawford, A. C. Walls, M. N. Pham, C. Chen, K.-L. Herpoldt, B. Fiala, M. Murphy, D. Pettie, J. C. Kraft, K. D. Malone, M. J. Navarro, C. Ogohara, E. Kepl, , N. P. King

This paper designs stabilized SARS-CoV-2 RBD variants using deep mutational scanning and structure-based design, showing improved thermal stability and manufacturability for vaccine applications.

bioRxiv · May 15, 2021Microbiology

Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

A. C. Walls, M. C. Miranda, M. N. Pham, A. Schaefer, A. Greaney, P. S. Arunachalam, M.-J. Navarro, M. A. Tortorici, K. Rogers, M. A. O'Connor, L. Shireff, D. E. Ferrell, N. Brunette, E. Kepl, J. E. Bowen, , Veesler

This study shows that a SARS-CoV-2 RBD nanoparticle vaccine protects against SARS-CoV-2 and related sarbecoviruses, including variants, in mice and non-human primates.

bioRxiv · Mar 15, 2021Immunology