NINJA: an inducible genetic model for creating neoantigens in vivo
M. Damo, B. Fitzgerald, Y. Lu, M. Nader, I. William, J. Cheung, K. A. Connolly, G. G. Foster, E. Akama-Garren, D.-Y. Lee, G. P. Chang, V. Gocheva, L. M. Schmidt, A. Boileve, J. H. Wilson, , N. S. Joshi
The paper develops a genetic model called NINJA to create inducible neoantigens in mice, enabling controlled T cell responses without central tolerance.
bioRxiv · Jan 9, 2020 · PreprintImmunology