Author

I. William

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. Cui· 3 shared M. Damo· 3 shared N. S. Joshi· 3 shared B. Fitzgerald· 2 shared G. G. Foster· 2 shared I. Monroy· 2 shared K. A. Connolly· 2 shared A. Boileve· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersImmunology

C. Cui

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The PD-1 checkpoint receptor maintains tolerance of self-reactive CD8 T cell in skin

M. Damo, C. Cui, I. William, N. I. Hornick, D. Kwok, K. Clulo, W. E. Damsky, J. S. Leventhal, N. S. Joshi

The paper shows that PD-1+ CD8 T cells in healthy skin remain tolerant to self-antigens and prevent tissue damage through PD-L1 upregulation on myeloid cells.

bioRxiv · Jul 9, 2021 · PreprintImmunology

A reservoir of stem-like CD8 T cells in the tumor-draining lymph node maintains the ongoing anti-tumor immune response

K. A. Connolly, M. Kuchroo, A. Venkat, A. Khatun, J. Wang, I. William, N. Hornick, B. Fitzgerald, M. Damo, M. Y. Kasmani, C. Cui, E. Fagerberg, I. Monroy, A. Hutchins, J. F. Cheung, , N. S. Joshi

The paper identifies a reservoir of stem-like CD8 T cells in tumor-draining lymph nodes that sustain anti-tumor immunity by maintaining TCF1 expression and resisting terminal differentiation.

bioRxiv · Jan 27, 2021Immunology

NINJA: an inducible genetic model for creating neoantigens in vivo

M. Damo, B. Fitzgerald, Y. Lu, M. Nader, I. William, J. Cheung, K. A. Connolly, G. G. Foster, E. Akama-Garren, D.-Y. Lee, G. P. Chang, V. Gocheva, L. M. Schmidt, A. Boileve, J. H. Wilson, , N. S. Joshi

The paper develops a genetic model called NINJA to create inducible neoantigens in mice, enabling controlled T cell responses without central tolerance.

bioRxiv · Jan 9, 2020 · PreprintImmunology