Author

K. A. Connolly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. Cui· 3 shared J. Wang· 3 shared M. Damo· 3 shared N. S. Joshi· 3 shared B. Fitzgerald· 2 shared E. Fagerberg· 2 shared G. G. Foster· 2 shared H. Zhao· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

C. Cui

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

WNK kinases sense molecular crowding and rescue cell volume via phase separation

C. R. Boyd-Shiwarski, D. J. Shiwarski, S. E. Griffiths, R. T. Beacham, L. Norrell, D. E. Morrison, J. Wang, J. R. Mann, W. Tennant, E. N. Anderson, J. Franks, M. Calderon, K. A. Connolly, C. J. Weaver, C. C. Weckerly, , A. R. Subramanya

This study shows WNK1 senses molecular crowding by phase separation to activate volume recovery in hypertonic conditions through phosphorylation-dependent signaling.

bioRxiv · Jan 10, 2022Cell Biology

A reservoir of stem-like CD8 T cells in the tumor-draining lymph node maintains the ongoing anti-tumor immune response

K. A. Connolly, M. Kuchroo, A. Venkat, A. Khatun, J. Wang, I. William, N. Hornick, B. Fitzgerald, M. Damo, M. Y. Kasmani, C. Cui, E. Fagerberg, I. Monroy, A. Hutchins, J. F. Cheung, , N. S. Joshi

The paper identifies a reservoir of stem-like CD8 T cells in tumor-draining lymph nodes that sustain anti-tumor immunity by maintaining TCF1 expression and resisting terminal differentiation.

bioRxiv · Jan 27, 2021Immunology

Neoantigen-driven B cell and CD4+ T follicular helper cell collaboration promotes robust anti-tumor CD8+ T cell responses

C. Cui, J. Wang, P.-M. Chen, K. A. Connolly, M. Damo, E. Fagerberg, S. Chen, S. C. Eisenbarth, H. Zhao, J. Craft, N. S. Joshi

This study shows that TFH-B cell interactions driven by neoantigens enhance anti-tumor CD8+ T cell responses in lung adenocarcinoma.

bioRxiv · Dec 23, 2020Immunology

NINJA: an inducible genetic model for creating neoantigens in vivo

M. Damo, B. Fitzgerald, Y. Lu, M. Nader, I. William, J. Cheung, K. A. Connolly, G. G. Foster, E. Akama-Garren, D.-Y. Lee, G. P. Chang, V. Gocheva, L. M. Schmidt, A. Boileve, J. H. Wilson, , N. S. Joshi

The paper develops a genetic model called NINJA to create inducible neoantigens in mice, enabling controlled T cell responses without central tolerance.

bioRxiv · Jan 9, 2020 · PreprintImmunology