Author

A. Brandt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 5 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Assay:whole-genome sequencing· 3 Research Focus:clustering· 2 Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 2

Frequent Co-Authors

J. Bast· 3 shared S. Scheu· 3 shared T. Schwander· 3 shared B. Heimburger· 2 shared I. Schaefer· 2 shared M. Labedan· 2 shared M. Maraun· 2 shared Z. Dumas· 2 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersEvolutionary Biology

J. Bast

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Identification of a targetable ST2-expressing fibroblast subset driving Peutz-Jeghers syndrome polyposis

E. Domenech-Moreno, W.-W. Lim, A. Brandt, T. Lemmetyinen, E. Viitala, T. P. Makela, S. Cook, S. Ollila

This study identifies ST2-expressing fibroblasts as drivers of Peutz-Jeghers syndrome polyposis and shows IL-11 as a therapeutic target.

bioRxiv · Nov 29, 2023 · PreprintCancer Biology

Haplotype independence contributes to evolvability in the long-term absence of sex in a mite

H. Oztoprak, S. Gao, N. Guiglielmoni, A. Brandt, Y. Zheng, C. Becker, K. Becker, V. Bednarski, L. Borgschulte, K. A. Burak, A.-M. Dion-Cote, V. Leonov, L. Opherden, S. Shimano, J. Bast

The paper identifies haplotypic independence as a mechanism enabling long-term survival of an asexual mite species without sex.

bioRxiv · Sep 7, 2023 · PreprintEvolutionary Biology

Evolution of alternative reproductive systems in Bacillus stick insects

G. Lavanchy, A. Brandt, M. Bastardot, Z. Dumas, M. Labedan, M. Massy, W. Toubiana, P. TranVan, A. Luchetti, V. Scali, B. Mantovani, T. Schwander

The paper re-evaluates reproductive modes in Bacillus stick insects using genomic and field data, confirming hybrid lineage ancestry and genome elimination mechanisms.

bioRxiv · Jul 31, 2023 · PreprintEvolutionary Biology

Convection and extracellular matrix binding control interstitial transport of extracellular vesicles

P. A. Sariano, R. Mizenko, V. S. Shirure, A. Brandt, C. Nesiri, B. Shergill, D. M. Rocke, R. P. Carney, S. C. George

This study shows that convection and ECM binding are the main mechanisms controlling EV transport in interstitial fluid, with implications for nanotherapeutic design.

bioRxiv · Aug 3, 2022Bioengineering

Rapid diversification of the Australian Amitermes group during late Cenozoic climate change

B. Heimburger, L. Schardt, A. Brandt, S. Scheu, T. R. Hartke

This study examines the diversification of the Australian Amitermes Group during late Cenozoic climate change, finding two pulses of rapid diversification linked to climate shifts.

bioRxiv · Apr 12, 2021Evolutionary Biology

Haplotype divergence supports ancient asexuality in the oribatid mite Oppiella nova

A. Brandt, P. Tran Van, C. Bluhm, Y. Anselmetti, Z. Dumas, E. Figuet, C. M. Francois, N. Galtier, B. Heimburger, K. S. Jaron, M. Labedan, M. Maraun, D. J. Parker, M. Robinson-Rechavi, I. Schaefer, , J. Bast

The paper uses genomic and transcriptomic data to show haplotype divergence patterns in asexual and sexual mite species, supporting ancient asexuality in Oppiella nova.

bioRxiv · Dec 7, 2020Evolutionary Biology

Effective purifying selection in ancient asexual oribatid mites

A. Brandt, I. Schaefer, J. Glanz, T. Schwander, M. Maraun, S. Scheu, J. Bast

The paper compares purifying selection effectiveness in asexual and sexual oribatid mite lineages, finding stronger selection in asexuals despite no sex.

bioRxiv · Mar 7, 2017Evolutionary Biology